Sir Rhys Mansel (c. 1487 – 1559), also Sir Rice Mansel, also Sir Rice Manxell, also Sir Rice Maunsell, Vice-Admiral, was High Sheriff of Glamorgan, a Commissioner of Peace and served as Chamberlain of Chester to King Henry VIII of England.
Sir Rice owned estates at Penrice and Oxwich, and at the Dissolution of the Monasteries he purchased Margam Abbey, which remained the property of his descendants until 1941.
He was High Sheriff of Glamorgan for 1542.